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Listeria monocytogenes Meningoencephalitis in Immunocompetent Patient-Clinical Course and Outcome

Listeria monocytogenes is the third most frequent cause of bacterial meningitis. It was an unusual etiological agent in immunocompetent patients. We described a 29-yearsold male patient with L. monocytogenes sepsis with meningoencephalitis hospitalized in the Clinic of Infectious Diseases, University Multiprofile Hospital of Active Treatment, Stara Zagora, Bulgaria. His initial complaints were headache, nausea and vomiting. At the admission, clinical examination showed severe meningeal irritation-neck stiffness and signs of Brudzinski, Kernig and Babinski. Cerebrospinal fluid (CSF) was slightly opalescent with changes as with viral infection of the central nervous system (CNS). Causative agent L. monocytogenes was proven from CSF and blood. The disease was very severe. Changes in consciousness and acute respiratory and cardiovascular failure imposed a two-month stay in intensive care unit. The patient was discharged after a hospital stay of 125 days. Within two years thereafter he was fully recovered without residual manifestations


Pekova L, Parusheva P, Rachkova K, Naydenov K, Tsoneva V and Mitev M

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