Isolation of Pathogens Causing Sepsis, Pus and Infected Wounds from Critical Care Unit: A Retrospective Study

Postsurgical wound infections are one of the important cause of morbidity and mortality worldwide. Therefore A retrospective study was conducted to evaluate microorganisms responsible for wound infections and their patterns of antibiotic sensitivity and resistance. In imparting a summarized analysis of wound microbiology, together with current opinion and controversies respecting wound evaluation and treatment, this review has attempted to acquire and approach microbiological aspects that are influential to the management of microorganisms in wounds. Study was designed on retrospective data of past two years from Intensive Care Units of public and private Health Care Sector of Critically Ill patients in which 200 isolates were obtained. Identification, isolation and antimicrobial susceptibility checking of isolates were done by using standard microbiological techniques. The most common pathogens isolated from wound and sepsis were staph aureus and coagulase negative staph.The potential microorganisms isolated were gram positive cooci (Beta haemolytic streptococci, Erthrococci, Staphylococci), gram negative aerobic rods (Enterobacter species, Escherchia coli, Klebsieela species), anaerobes (Bacteroides, Clostridium) fungi (Yeasts, Aspergillus). Most of the pathogens are susceptible to vancomycin and ciprofloxacin that is 36.3% and 33.40% respectively while the most resistant drug was ceftriaxone. The culture sensitivity tests showed that numerous and multi drug resistant microorganisms are involved in wounds infection and sepsis. By determining a coefficient approach to the microbiological management of wound complications, meaningful savings in cost and time (i.e., nursing, medical, and microbiological) may be captured while allowing prompt and suitable treatment for the patient.


Maria Ayub, Huma Rizwan, Safina Siddique and Ushna Maryam

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