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Peritonitis Following Pre-Pyloric Ulcer Perforation: a Case Report

Seyed Farshad Heidari*

Department of Emergency Medicine, Emam Khomeini Hospital, Medical Faculty, Mazandaran University of Medical Sciences, Sari, Iran.

*Corresponding Author:
Seyed Farshad Heidari
Department of Emergency Medicine, Emam Khomeini Hospital
Medical Faculty, Mazandaran University of Medical Sciences, Sari, Iran.
Tel: +981133355080
E-mail: [email protected]

Received Date: June 01, 2017; Accepted Date: June 26, 2017; Published Date: July 04, 2017

Citation: Heidari SF (2017) Peritonitis Following Pre-Pyloric Ulcer Perforation: A Case Report. Ann Clin Lab Res 5: 2

Visit for more related articles at Annals of Clinical and Laboratory Research


Peritonitis due to peptic ulcer perforation is a surgical emergency with a high risk of mortality and morbidity. A case was presented here, that is a 19-year-old man who underwent an emergency laparotomy for peritonitis caused by perforation of peptic ulcer without risk factor for PUD. The ulcer was located on the pre-pyloric region, close to the lesser curvature. This case report highlights the importance of maintaining a high clinical suspicion of a perforated peptic ulcer in patients presenting with an acute abdomen without risk factor for peptic ulcer.


Peritonitis; Peptic ulcer; Perforation; Case report


Perforation of the gastrointestinal tract is one of the lifethreatening causes of acute abdomen that presenting with acute abdominal pain and severe distress of the patient. In one third of patients, the presentation is less obvious, resulting in significant delays in diagnosis of peritonitis. Peritonitis due to perforation of the GI tract is a common surgical emergency allover the world [1], that occurs in about 2% to 14% of patients with active ulcer disease [2,3]. Surgical treatment of perforation peritonitis strongly recommended and included combination of improved surgical technique, anti-microbial therapy and intensive care support has improved the outcome of such cases [4]. The aim of this case report is presentation of a case with gastric perforation without apparent manifestation and risk factor for peptic ulcer disease (PUD).

Case report

A 19-year-old man presented to the emergency department with a history of abdominal pain, nausea and anorexia from 4- days ago. Abdominal pain was periodic during this period. There was history of sudden pain in the upper abdomen on the 4th day that was persistent. Abdominal pain was in severe grade and not relieved by medication. His job was soldier that was started from one-year-ago. In past medical history, the patient had significant history of epigastric pain from the last 12-months without diagnostic evaluation for its cause. He has no history of smoking or drinking alcohol. Drug history was negative. On admission, he had the normal appearance with blood pressure 110/70 mmHg, pulse rate 85 beats per minute and temperature of 37.1°C. Abdominal examination revealed generalized tenderness. Also, guarding and rigidity were present and occasional bowel sounds were also noted. Other examinations were normal. Plain upright chest X-ray demonstrated excessive free gas under both hemi-diaphragms that has been showed in Figure 1. Preoperative laboratory investigations were in normal range with Hb (15 g/dL), renal function test (serum urea, 35 mg/L; serum creatinine, 1.1 mg/dL) and electrolytes (serum sodium, 140 meq/L, serum potassium, 4.2 meq/L). The broad-spectrum antibiotics, a combination of injectable third generation cephalosporin and metronidazole, were administered for patient. After initial resuscitation (placement of intravenous lines and nasogastric tube followed by adequate administration of fluids), the patient underwent an emergency exploratory laparotomy. During laparotomy, one gastric perforation was identified in the pre-pyloric region, close to the lesser curvature, that the perforations were repaired. Post-operative period was smooth. Patient was discharged on the 7th post-operative day. common complication [5], that often present with acute abdomen. Although perforated peptic ulcer frequently is considered a rather benign condition, but it is a lifethreatening complication that carries high risk for morbidity and mortality [6]. The number of patients admitted for emergency surgery after peptic ulcer perforation has not undergone a similar decline, and peptic ulcer perforation remains a substantial healthcare problem [7]. Peptic perforation is most commonly present in the first part of the duodenum (35% to 65%), with 25% to 45% located in the pylorus, and 5% to 25% in the stomach [1]. The etiological factors responsible for peptic perforation vary depending upon sociodemographic factors [8-10]. GI perforation occurs often secondarily to an underline disease, particularly, acute diverticulitis, acute appendicitis, gastric and duodenal ulcers, ischemic colitis and inflammatory bowel disease (IBD) [8]. The factors that participate frequently in occurrence of peptic perforation are helicobacter pylori infection and chronic use of NSAIDs [9]. Other factors influencing in GI perforation generally occurs as a result of stress, excessive smoking, and consumption of alcohol or coffee [10]. The best surgical option for these patients is simple closure with omental patch. It is the easiest, quickest and safest operation, and can be applied to all situations by every surgeon. In this patient who was introduced here, as regards the symptoms of perforation were not evident, the patient presented to hospital with delayed. Also as respects the patient had no risk factors for perforation. Peptic ulcer diseases even cases are complicated when presented in young age has many causes that must be examined include zollinger-ellison disease, behcet's disease, drug addiction, lymphoma and etc.


Figure 1: Chest x ray (upright) in patient with perforated prepyloric ulcer. Plain upright chest x-ray demonstrated excessive free gas under both hemi-diaphragms.


Perforated peptic ulcer is not rare and it is relatively simple to have the diagnosis that needs to immediate treatment.


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