Figure 4: Mitochondrial bioenergetics in isolated mitochondria from red skeletal muscle from MCK-APP and wild type mice. (A) Respiratory control ratio, (B) State 2 respiration rate, (C) State 3 (ADP stimulated) respiration rate, (D) state 4o (oligomycin insensitive) respiration rate, and (E) state 3u (FCCP-stimulated) respiration rate.