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Post Thrombolysis Intracranial Hemorrhage

Ayush Dubey*

Department of Neurology, SAIMS Medical College and PG Institute, Indore, Madhya Pradesh, India

*Corresponding Author:
Ayush Dubey
Department of Neurology
SAIMS Medical College and PG Institute
Indore, Madhya Pradesh, India
Tel: +917999867326

Received Date: April 03, 2018; Accepted Date: April 20, 2018; Published Date: April 24, 2018

Citation: Dubey A (2018) Post Thrombolysis Intracranial Hemorrhage. Ann Clin Lab Res Vol.6: No.2:232.

Visit for more related articles at Annals of Clinical and Laboratory Research


Intra cranial hemorrhage is a major complication of thrombolytic therapy in acute ischemic stroke which is also associated with high mortality. It typically occurs within 24-36 hours of treatment initiation and is characterized by rapid hematoma development and growth [1]. The most consistently identified predictors of clinically significant ICH in acute revascularization trials have been thrombolytic therapy, dose of lytic agents, edema or mass effect on head CT, stroke severity, and age. Other risk factors may be hyperglycemia, concurrent heparin use, timing of therapy, and timing of successful recanalization [2,3] (Figures 1 and 2).


Figure 1: Baseline CT scan done immediately after stroke.


Figure 2: CT scan after tissue plasminogen activator (alteplase) showing massive intracranial hemorrhage in left fronto parietal region.


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