Reach Us +1-8507546199
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.


Hepatocellular Carcinoma during HIV/HBV Co-Infection

HIV/HBV Co-infection constitute a public health problem in sub-Saharan Africa. Its prognosis is high because of late diagnosis. We are reporting a case of HIV/ HBV co-infection detected at the stage of hepatocellular carcinoma with the aim of contributing to a better care for cases of HBV and HIV co-infection. This is about a 43 year-old adult co-infected with HBV and HIV-1. Upon admission into the Department of Infectious Diseases, the review noted a maintained general condition, an icteric conjunctiva, a conjunctival pallor, a weight equal to 60 kg, there was neither dehydration, any hepato splenomegaly or collateral venous circulation. Laboratory tests showed moderate immunosuppression (CD4 = 260/ mm3), moderate anemia (Hb rate = 11, 4 g/dl), thrombocytopenia (platelets = 127 000 /mm3), high alpha fetoproteins (1800 U/ml), on fibrotest the fibrosis score was equal to 0.9 and the activity score to 0.9; Gamma GT = 91 U/l, total Bilirubin = 81.11 micromol/l (N <25.7), a prothrombin rate = 71.70% (N = 70-100), IgM antiHBc = negative. Hepatic ultrasound objectified appearance compatible with cirrhosis. The diagnosis is a post viral hepatitis B hepatocellular carcinoma complicating cirrhosis.

HBV/HIV co-infection is serious because of the rapid progression to cirrhosis and hepatocellular carcinoma. Routine screening of viral hepatitis B which is an AIDS marker in HIV-positive people will allow a holistic medical care, necessary to prevent hepatocellular carcinoma


Savadogo M, Boushab MB and Fall-Malick FZ

Abstract | Full-Text | PDF

Share this  Facebook  Twitter  LinkedIn  Google+
Flyer image

Abstracted/Indexed in

  • Index Copernicus
  • Google Scholar
  • Genamics JournalSeek
  • China National Knowledge Infrastructure (CNKI)
  • CiteFactor
  • Directory of Research Journal Indexing (DRJI)
  • Publons
  • Secret Search Engine Labs