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Abstract

Are Albumin and Lactate Predictive Indicators for Mortality in Critically Ill Patients with Acute Kidney Injury?

Introduction: The aim of this study was to assess the effect of age, gender, estimated glomerular filtration rate, albumin and lactate on mortality on critically ill patients admitted to intensive care unit due to acute kidney injury.

Methods: The study included 54 critically ill patients over the age of 18, who were admitted to our Level 3 intensive care unit with the diagnosis of acute kidney injury. Patients were divided into two groups as those who did not develop mortality (Group 1) and those who developed (Group 2). Both groups were compared in terms of age, gender, estimated glomerular filtration rate, albumin and lactate levels in the first 24 hours of admission. In addition, patients were divided into two groups according to both albumin levels (<2.5 g/dL and ≥2.5 g/dL) and lactate levels (<2 mmol/L and ≥2 mmol/L) and examined in terms of 30-day mortality.

Results: The patients’ total mortality was 68.5% (37 patients). There was no statistically significant difference between the two groups (Group 1 and Group 2) in terms of age, sex, estimated glomerular filtration rate, albumin and lactate levels (p-values, respectively: 0.13; 0.39; 0.32; 0.83; 0.52). In addition, there was no statistically significant difference between the groups in terms of 30- day mortality (p-values: 0.625; 0.127).

Conclusion: Age, gender, estimated glomerular filtration rate, albumin and lactate levels did not affect 30-day and total mortality in our patients who were hospitalized in our intensive care unit with acute kidney injury diagnosis, and that albumin and lactate levels during admission were not a predictor of mortality in this patient group.


Author(s):

Cem Kivilcim Kacar* and Osman Uzundere



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